Eritropoietina utile per combattere la SLA

di

Una preliminare ricerca tutta italiana, condotta dagli scienziati dell’Istituto Neurologico Besta di Milano grazie ai fondi messi a disposizione di ARISLA (Agenzia di RIcerca per la Sclerosi Laterale Amiotrofica), avrebbe dimostrato, in via del tutto teorica, la possibilità che l’EPO, la famigerata eritropoietina utilizzata come dopante da ciclisti, calciatori e la quasi totalità degli sportivi di qualsiasi genere, possa curare, o per lo meno rallentare in maniera significativa, la Sclerosi Laterale Amiotrofica.

► SLA: MANCATO RICICLAGGIO NEURONI


L’idea di provare ad utilizzare l’EPO per far fronte alla degenerazione dei neuroni provocata proprio dalla SLA, comunque, non è nuova. Soltanto oggi, però, si sarebbero evidenziate abbastanza occorrenze scientifiche che giustificherebbero l’inizio di una fase sperimentale.

Adesso, dunque, partiranno i trials clinici, che si evince saranno condotti su una 50ina di volontari affetti dalla terribile patologia, il cui scopo sarà quello di convalidare le ipotesi dei ricercatori nonché di individuare le dosi dell’ormone che qualunque paziente possa tollerare così che la cura possa essere considerata efficacie senza per questo essere dannosa.

► SPIRULINA PER COMBATTERE LA SLA

Inoltre, se possibile, grazie allo studio si cercheranno di individuare con chiarezza i meccanismi di funzionamento dell’EPO nonché della malattia vera e propria.

Lo scopo dichiarato, dunque, non è soltanto quello di curare la malattia bensì di individuare dei marcatori che possano far individuare precocemente la suddette patologia e, dunque, attivare tutta una serie di comportamenti preventivi e strategie terapeutiche che possano scongiurare l’insorgenza della SLA o limitarne sul nascere gli effetti negativi.

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    What got me on it was honestly pretty stupid — I could never get my head round what an ew return would be with 1/5 odds a place. I’d just wing it and moan when the payout landed. These days I punch the numbers in before I place anything, even the boring singles.

    Their single bet calculator tool is the bit I open most — type in your stake, the odds and it spits out returns with no faffing, fractions or decimals. It also handles the multiples — acca and treble returns, a lucky 15, a yankee, which is where most people I know got it wrong. If you fancy a poke about, it’s over at sports betting margin calculator — free, no signup.

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    Couple of gripes. The design looks a bit basic — zero frills, it’s clearly function over form. Phone-wise it’s usable although the bigger tables are a squeeze. And no app, it’s a website and that’s it — slight shame but you asked.

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    How I found it was genuinely embarrassing — I never could figure out what an e/w return would be with 1/5 odds a place. I’d just eyeball it and then be surprised. Now type the odds in before every slip, even a simple single bet.

    The single bet calculator tool is the part I use most — you drop in stake and odds and it shows returns instantly, either odds format. There’s also the fiddly ones — trebles maths, lucky 15 and lucky 63, patents and yankees, honestly that’s where I’d always lose track. If you fancy a poke about, it lives at accum calculator and it’s free with no account nonsense.

    One thing that genuinely made a difference was the geekier extras. The implied probability calculator and it makes obvious what margin’s baked in, and there’s the kelly staking calculator — I use half kelly since full stakes are far too aggressive. The dutching one is decent if I’m spreading across selections.

    Couple of gripes. Its interface looks a bit basic — no flash, which honestly I don’t mind but some will. Phone-wise it’s fine but the lucky 63 breakdown make you pinch and zoom. And no proper app, it’s browser only — doesn’t bother me but worth saying.

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  191. OK — been on this thing for maybe a few months now and it’s stuck on my phone, so figured I’d say something since a mate asked me the other day. Am UK based, mainly do football and horses, small stakes, for context.

    How I found it was honestly a bit daft — I could never figure out what an e/w payout actually came to when the place terms changed. I’d just wing it and get a shock. Now type the odds in before every slip, even a straight one-selection punt.

    The single bet calculator is the one I’m on daily — you put in stake and odds and it shows the return straight away, either odds format. It also handles the fiddly ones — trebles maths, lucky 15 and lucky 63, a yankee, honestly that’s where I always got it wrong. If you want a look, it’s over at ew single — free, no signup.

    What genuinely changed how I bet is the nerdier extras. They’ve got an implied probability calculator and it makes obvious how much the bookie’s taking, plus a kelly staking tool — I use half kelly because full kelly is terrifying. The dutch tool is decent when I’m covering two or three runners.

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