Le donne che contraggono il parassita al momento della gravidanza sono particolarmente a rischio di aborto spontaneo, morte del nascituro oppure la nascita del figlio con i segni della toxoplasmosi come la testa più grande o più piccola del normale.
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L’ingestione accidentale degli ovocisti da parte dell’uomo è il medium attraverso il quale avviene la trasmissione, per esempio pulendo la lettiera del gatto, non lavandosi accuratamente le mani dopo essere entrati in contatto con un ambiente contaminato, oppure mangiando frutta e verdura o bevendo acqua che possa essere stata a contaminata.
Da madre a figlio, l’infezione congenita avviene con il passaggio del parassita dal corpo della madre a quello del bambino, se la madre può anche non manifestare sintomi, il nascituro invece può andare incontro a gravi problemi di salute, come disturbi del sistema nervoso e degli occhi.
Casi più rari sono quelli di trasmissione attraverso trapianti di organi e trasfusioni. Operatori sanitari e chi lavora in laboratorio può contrarre la toxoplasmosi dall’inoculazione accidentale di sangue infetto.
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