Acalasia

di

Esofagite e cura

L’acalasia (dal greco mancato rilasciamento), da non confondere con la calasia, è la più comune patologia motoria primitiva dell’esofago. La malattia è caratterizzata dalla perdita progressiva della peristalsi esofagea e dalla incapacità di rilasciamento dello Sfintere esofageo inferiore (LES), posto al confine tra esofago e stomaco. Il ruolo fisiologico del LES è quello di impedire il reflusso del contenuto gastrico nell’esofago. Normalmente, durante la deglutizione, lo sfintere si rilascia, consentendo la progressione del bolo alimentare nello stomaco. In caso di acalasia, il LES resta sempre tonico e il rilasciamento è incompleto, per cui si verifica ristagno di materiale alimentare nel lume esofageo. Tale ristagno provoca una progressiva dilatazione dell’esofago, tanto che la malattia è anche denominata megaesofago.

L’acalasia ha una prevalenza di 1/10.000, senza differenze tra i due sessi e con la massima frequenza tra i 30 e i 50 anni.

È dovuta a un’anomala innervazione della muscolatura liscia dell’esofago. Tre sono i possibili meccanismi:

patologia infettiva neurotropa (come malattia di Chagas l’agente è noto essere il Tripanosoma cruzii)

degenerazione dei plessi intramurali (plesso di Auerbach)

disordine infiammatorio autoimmune.

Ci sono inoltre forme di disautonomia familiare in cui si hanno anche alterazioni del sistema nervoso autonomo.

È riportata l’associazione di acalasia con insufficienza surenalica e assenza di lacrimazione (sindrome di Allgrave).

Sintomi

Il sintomo cardinale della acalasia è la disfagia (sensazione di arresto del bolo alimentare nell’esofago). La disfagia si manifesta sia per i liquidi che per i solidi, ma inizialmente può essere paradossa, perché il paziente deglutisce bene i solidi, ma non i liquidi, in quanto i solidi grazie al loro maggior peso possono progredire più facilmente lungo l’esofago, anche in assenza di peristalsi.

Gli altri sintomi comprendono: rigurgito di cibo indigerito nel 70% dei casi, soprattutto notturno, favorito dal decubito; tosse notturna, causata dal rigurgito che può penetrare nelle vie respiratorie; polmonite ab ingestis, una complicazione del precedente sintomo; scialorrea (eccessiva salivazione); alitosi, poiché il cibo che ristagna nell’esofago fermenta e dà alitosi; dolore toracico e pirosi possono essere presenti nel 30% dei casi, quale conseguenza di aumentata pressione esofagea o esofagite da stasi. Un altro sintomo è la perdita di peso.

 

1.669 commenti su “Acalasia”

  1. Thanks for the strategies you write about through this website. In addition, lots of young women which become pregnant tend not to even try to get health care insurance because they have anxiety they couldn’t qualify. Although a few states right now require that insurers offer coverage despite the pre-existing conditions. Prices on these types of guaranteed programs are usually larger, but when considering the high cost of health care it may be a safer strategy to use to protect one’s financial potential.

  2. I’m typically to running a blog and i really admire your content. The article has actually peaks my interest. I’m going to bookmark your website and preserve checking for brand spanking new information.

  6. I have realized that online diploma is getting favorite because attaining your college degree online has changed into a popular selection for many people. Many people have never had a possible opportunity to attend a normal college or university nonetheless seek the elevated earning possibilities and career advancement that a Bachelor’s Degree gives. Still others might have a qualification in one field but would wish to pursue some thing they already have an interest in.

  8. I really like your blog.. very nice colors & theme. Did you make this website yourself or did you hire someone to do it for you? Plz respond as I’m looking to design my own blog and would like to find out where u got this from. cheers

  9. Thanks for your post. I also feel that laptop computers are becoming more and more popular these days, and now tend to be the only type of computer used in a household. This is due to the fact that at the same time actually becoming more and more economical, their processing power is growing to the point where they may be as potent as desktop computers coming from just a few in years past.

  11. Have you ever thought about creating an ebook or guest authoring on other sites? I have a blog based upon on the same topics you discuss and would love to have you share some stories/information. I know my readers would appreciate your work. If you’re even remotely interested, feel free to shoot me an email.

  22. We’re a group of volunteers and starting a brand new scheme in our community. Your website offered us with useful information to paintings on. You have done an impressive process and our entire group shall be thankful to you.

  23. Hey There. I found your blog using msn. This is a really well written article. I will be sure to bookmark it and come back to read more of your useful info. Thanks for the post. I?ll definitely comeback.

  24. Wonderful blog! Do you have any suggestions for aspiring writers? I’m hoping to start my own blog soon but I’m a little lost on everything. Would you propose starting with a free platform like WordPress or go for a paid option? There are so many options out there that I’m totally confused .. Any tips? Thanks a lot!

  26. I have observed that in the world the present moment, video games are definitely the latest craze with children of all ages. Periodically it may be difficult to drag your son or daughter away from the games. If you want the best of both worlds, there are several educational gaming activities for kids. Interesting post.

  41. Great write-up, I am normal visitor of one?s website, maintain up the nice operate, and It is going to be a regular visitor for a long time.

  43. Somebody essentially help to make seriously articles I would state. This is the first time I frequented your web page and thus far? I amazed with the research you made to make this particular publish extraordinary. Excellent job!

  44. Wonderful site. Lots of useful info here. I am sending it to a few friends ans also sharing in delicious. And of course, thanks for your effort!

  45. I might also like to say that most individuals that find themselves without having health insurance are normally students, self-employed and people who are not working. More than half with the uninsured are really under the age of Thirty five. They do not feel they are requiring health insurance simply because they’re young along with healthy. Their particular income is often spent on housing, food, in addition to entertainment. Most people that do work either complete or not professional are not provided insurance via their work so they get along without as a result of rising cost of health insurance in the usa. Thanks for the tips you reveal through this web site.

  47. I have realized that online degree is getting favorite because attaining your degree online has changed into a popular selection for many people. Quite a few people have definitely not had an opportunity to attend a traditional college or university but seek the raised earning possibilities and a better job that a Bachelor’s Degree gives. Still others might have a college degree in one course but would like to pursue anything they already have an interest in.

  48. Fantastic blog! Do you have any recommendations for aspiring writers? I’m hoping to start my own website soon but I’m a little lost on everything. Would you advise starting with a free platform like WordPress or go for a paid option? There are so many choices out there that I’m totally overwhelmed .. Any ideas? Thanks a lot!

  54. The subsequent time I read a blog, I hope that it doesnt disappoint me as a lot as this one. I imply, I do know it was my choice to read, however I truly thought youd have one thing attention-grabbing to say. All I hear is a bunch of whining about one thing that you possibly can repair should you werent too busy searching for attention.

  70. of course like your web site however you need to test the spelling on quite a few of your posts. Several of them are rife with spelling issues and I to find it very troublesome to tell the truth then again I will certainly come again again.

  73. Wow that was unusual. I just wrote an extremely long comment but after I clicked submit my comment didn’t appear. Grrrr… well I’m not writing all that over again. Anyway, just wanted to say superb blog!

  77. Thanks for this glorious article. Also a thing is that almost all digital cameras come equipped with the zoom lens that allows more or less of the scene to get included by simply ‘zooming’ in and out. All these changes in {focus|focusing|concentration|target|the a**** length are usually reflected within the viewfinder and on large display screen right at the back of your camera.

  78. Thanks for expressing your ideas. The one thing is that pupils have an alternative between federal student loan plus a private student loan where it’s easier to go with student loan debt consolidation reduction than with the federal student loan.

  91. I have been surfing online more than three hours as of late, but I never discovered any interesting article like yours. It?s pretty value enough for me. In my view, if all webmasters and bloggers made just right content as you did, the web can be much more useful than ever before.

  92. Thank you for sharing excellent informations. Your web-site is so cool. I’m impressed by the details that you?ve on this site. It reveals how nicely you understand this subject. Bookmarked this web page, will come back for more articles. You, my friend, ROCK! I found just the info I already searched all over the place and just couldn’t come across. What an ideal site.

  93. One other issue issue is that video games are normally serious as the name indicated with the major focus on mastering rather than leisure. Although, there is an entertainment facet to keep your children engaged, every game is often designed to work on a specific expertise or program, such as mathematics or scientific disciplines. Thanks for your article.

  94. You can definitely see your skills in the paintings you write. The world hopes for even more passionate writers like you who are not afraid to say how they believe. Always go after your heart.

  95. Wonderful items from you, man. I’ve understand your stuff previous to and you are just too great. I really like what you have bought right here, certainly like what you are saying and the way in which in which you are saying it. You are making it enjoyable and you still take care of to stay it sensible. I can’t wait to learn much more from you. That is really a tremendous site.

  105. Hi, Neat post. There is an issue together with your website in internet explorer, might test this? IE still is the market chief and a good component of people will leave out your fantastic writing because of this problem.

  107. It’s a pity you don’t have a donate button! I’d without a doubt donate to this fantastic blog! I guess for now i’ll settle for book-marking and adding your RSS feed to my Google account. I look forward to new updates and will share this site with my Facebook group. Chat soon!

  113. Great blog right here! Also your site so much up very fast! What host are you the usage of? Can I get your affiliate link in your host? I wish my site loaded up as quickly as yours lol

  118. This article is a breath of fresh air! The author’s distinctive perspective and perceptive analysis have made this a truly fascinating read. I’m appreciative for the effort she has put into crafting such an enlightening and mind-stimulating piece. Thank you, author, for offering your wisdom and sparking meaningful discussions through your outstanding writing!

  131. I cherished up to you’ll obtain carried out right here. The caricature is attractive, your authored subject matter stylish. nonetheless, you command get got an shakiness over that you would like be handing over the following. in poor health definitely come more in the past once more as precisely the similar just about a lot regularly inside of case you protect this increase.

  136. I am curious to find out what blog system you are working with? I’m experiencing some small security problems with my latest blog and I’d like to find something more safe. Do you have any suggestions?

  139. Thanks for the tips on credit repair on this web-site. Things i would advice people would be to give up the actual mentality that they may buy right now and pay later. As a society we tend to repeat this for many issues. This includes trips, furniture, as well as items we’d like. However, you should separate a person’s wants out of the needs. When you are working to boost your credit score actually you need some trade-offs. For example you possibly can shop online to save cash or you can go to second hand retailers instead of highly-priced department stores with regard to clothing.

  156. Thanks for your write-up. One other thing is the fact that individual states have their very own laws which affect house owners, which makes it quite difficult for the our elected representatives to come up with the latest set of recommendations concerning property foreclosure on property owners. The problem is that every state features own guidelines which may work in an adverse manner in relation to foreclosure insurance policies.

  158. That is the precise weblog for anyone who desires to find out about this topic. You understand a lot its virtually exhausting to argue with you (not that I truly would want?HaHa). You undoubtedly put a new spin on a subject thats been written about for years. Nice stuff, simply great!

  169. One other issue issue is that video games are generally serious naturally with the key focus on studying rather than amusement. Although, we have an entertainment element to keep the kids engaged, each one game will likely be designed to work on a specific group of skills or curriculum, such as math or scientific research. Thanks for your posting.

  170. Hello, i read your blog from time to time and i own a similar one and i was just wondering if you get a lot of spam comments? If so how do you prevent it, any plugin or anything you can suggest? I get so much lately it’s driving me mad so any support is very much appreciated.

  196. There are some interesting cut-off dates on this article but I don?t know if I see all of them heart to heart. There’s some validity but I will take hold opinion till I look into it further. Good article , thanks and we would like more! Added to FeedBurner as properly

  198. I think this is one of the most important info for me. And i am glad reading your article. But wanna remark on few general things, The site style is perfect, the articles is really great : D. Good job, cheers

Lascia un commento

Powered by  GDPR Cookie Compliance
Panoramica privacy

This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.